Myeloperoxidase exerts microbicidal activity against Mycobacterium tuberculosis.
نویسندگان
چکیده
We investigated the antimycobacterial role of myeloperoxidase (MPO), one of the most abundant granule proteins in human neutrophils. Our data indicate that purified MPO, in the presence of hydrogen peroxide, exerts a consistent killing activity against Mycobacterium tuberculosis H37Rv and against a clinical isolate. The activity is time and dose dependent and requires the presence of chloride ions in the assay medium.
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ورودعنوان ژورنال:
- Infection and immunity
دوره 67 8 شماره
صفحات -
تاریخ انتشار 1999